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Comparison of 24-h Oscillations between Wild-Type and tim01 Genotypes

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posted on 2013-02-22, 08:44 authored by Herman Wijnen, Felix Naef, Catharine Boothroyd, Adam Claridge-Chang, Michael W Young

(A) Direct comparison between value-ordered wild-type and tim01 24-h Fourier scores. The upward trend represents a clock-dependent enrichment in high-quality circadian oscillations. The same format is used here as for Figure 2A except that the tim01 Fourier scores take the place of the permutation background model. To compare equal numbers of days in both genotypes, four days of data (2× LD/DD) are used on each axis.

(B and C) QQ plots comparing the data in panel (A) to a permutation null model (method as in Figure 2A). (B) Comparison of wild-type data to the permutation null model shows that the enrichment in Fig. 2A persists (although somewhat damped) with half the amount of data (2xLD/DD). (C) Comparison of tim01 data (2× LD/DD) to the permutation null model shows that 24-h oscillations, if present, are not obviously enriched in the absence of a working circadian clock.

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