<i>Clec4f−/−</i> mice showed a similar response of α-GalCer induced activation to wild-type mice <i>in vivo</i>.

<p>Both wild-type and <i>Clec4f−/−</i> littermates were treated with α-GalCer (1 µg/mouse) intravenously. Serum levels of (A) ALT and (B) cytokines, including IL-4 and IFN-γ were analyzed for samples taken at indicated time points after α-GalCer challenge. Data are representative of three independent experiments with similar results. (3 mice in each group).</p>