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Clec4f−/− mice showed a similar response of α-GalCer induced activation to wild-type mice in vivo.

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posted on 2013-06-06, 00:50 authored by Chih-Ya Yang, Jiun-Bo Chen, Ting-Fen Tsai, Yi-Chen Tsai, Ching-Yen Tsai, Pi-Hui Liang, Tsui-Ling Hsu, Chung-Yi Wu, Mihai G. Netea, Chi-Huey Wong, Shie-Liang Hsieh

Both wild-type and Clec4f−/− littermates were treated with α-GalCer (1 µg/mouse) intravenously. Serum levels of (A) ALT and (B) cytokines, including IL-4 and IFN-γ were analyzed for samples taken at indicated time points after α-GalCer challenge. Data are representative of three independent experiments with similar results. (3 mice in each group).

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