Chronic visual deprivation, from birth to adulthood, does not affect the density of estrogen-associated circuits in V1.

Shown are the mean numerical densities (± S.E.) of cells that are positive for ARO-, ERα- and ERβ-positive in the V1 of control (normally-raised) and light-deprived adult mice. Data is shown for supragranular, granular and infragranular layers separately. Light-deprived animals were born and kept in complete darkness until adulthood (see Methods). No differences were detected for ARO-, ERα- or ERβ, for any cortical layers, when comparing control and chronically light-deprived animals.