Figure_2.tif (1001.83 kB)
CHK1 and TEC knockdown and RRM1-dependent gemcitabine sensitivity.
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posted on 2013-03-05, 09:59 authored by Jun Zhou, Zhengming Chen, Agnes Malysa, Xin Li, Paula Oliveira, Yingtao Zhang, Gerold BeplerThe H23 and MCF7 cell line systems with increased (−R1) and reduced (−shR1) RRM1 expression were transfected with CHK1-specific or TEC-specific siRNA and exposed to gemcitabine. IC50 values are the mean of four replicates. CHK1 is depicted in green and red, TEC is depicted in blue and orange.
