Figure_2.tif (4.72 MB)
Bmp7 expression in Bmp7-lacZ mouse embryos at stage E13.5.
figure
posted on 2013-03-15, 09:17 authored by Thaleia Kouskoura, Anastasiia Kozlova, Maria Alexiou, Susanne Blumer, Vasiliki Zouvelou, Christos Katsaros, Matthias Chiquet, Thimios A. Mitsiadis, Daniel GrafWidespread transcriptional activity of Bmp7 is revealed by lacZ staining in the developing palate (A), the tongue (B, C), and the lower lip (D). Note the strong lacZ staining in the developing palatal rugae, the gustatory follicles and the midline of the lower lip (arrowhead). Weak Bmp7 expression is observed in Meckel's cartilage (arrows). (E–I) Bmp7 transcriptional activity appeared to be dynamic with some regional anteroposterior differences and could be detected both in palatal epithelium and mesenchyme (Fig. 2E–I; E anterior, I posterior). Scale bar, 50 μm.