Blockade of AT1 with losartan was not involved in the inhibitory effect of rosiglitzone on Ang II-induced KLF5 expression in VSMCs.

Western blot analysis (upper panel), and data are mean ± S.E.M. (bottom panel) of 3 independent experiments. Results are expressed as fold increase over control group. β-actin served as an internal control (*P<0.05 vs. control; #P<0.05 vs. Ang II).