Biomarker networks of immune system from cynomolgus macaques naturally infected with <i>T</i>. <i>cruzi</i> (CH) and non-infected controls (NI).

<p>Circular layouts were built to underscore the relevant associations between cell subsets, the expression of adhesion molecules, cytotoxicity markers, and the activation/regulatory status, using a clustered distribution of nodes for innate (left side) and adaptive (right side) immunity cells. The overall statistical analysis of the network node neighborhood connections points out to a uniform pattern in non-infected controls and a clear shift towards a bimodal profile in <i>T</i>. <i>cruzi</i>-infected hosts, with prominent involvement of adaptive immunity events.</p>