Antibody binding kinetic constants to selected MPER probes.
MPER peptide: EQELLELDKWASLWNWFDITKWLWYIKKKKGSKKK.b
Linked peptide: EQELLELDKWASLGGGGSGGWNWFDITKWLWYIKKKKGSKKK.c
ES2 scaffold: scaffold protein displaying the 2F5 gp41 epitope stabilized in the antibody-bound conformation.d
Association rate (kon) is measured in (1/Ms 105).e
Dissociation rate (koff) is measured in (1/s 10−3).f
Affinity constant (KD) is measured in (M 10−9 or nM).