Anaesthetic parameters of adult zebrafish when treated with propofol alone or combined with lidocaine.

a) equilibrium loss, b) loss of touch reaction, c) loss of reaction to a painful stimulus, and d) equilibrium recovery of adult zebrafish after being placed in an anaesthetic bath of 2.5, 5 or 7.5 μg/ml of propofol alone (P) or 2.5 μg/ml of propofol combined with 50, 100 or 150 μg/ml of lidocaine (P/L). Each point represents an animal. n = 10. Data are expressed as median [interquartile range]. * p< 0.05 compared with 2.5 μg/ml of propofol; ° p< 0.05 compared with all groups except with 5 μg/ml of propofol; ^#p< 0.05 compared with 5 μg/ml of propofol.