Figure_5.tif (560.85 kB)
Altered paired-pulse facilitation in mice lacking hippocampal and cortical primary cilia.
figure
posted on 2014-09-03, 03:11 authored by Nicolas F. Berbari, Erik B. Malarkey, S. M. Zaki R. Yazdi, Andrew D. McNair, Jordyn M. Kippe, Mandy J. Croyle, Timothy W. Kraft, Bradley K. YoderField recordings from CA1 hippocampus after schaffer collateral stimulation. (A) example traces of paired fEPSPs recorded in wild type (white) and mutant (black) hippocampal slices. (B) Cilia mutant neurons show an increase in paired pulse facilitation. (C) Long term potentiation recordings after 4 100 hz trains. Statistically significant differences are indicated: Student's t-test, * p<0.05.