Figure_3.tif (6.23 MB)
Aliphatic compounds act as linactants.
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posted on 2014-10-09, 03:06 authored by Jonathan Barnoud, Giulia Rossi, Siewert J. Marrink, Luca MonticelliLocalization of DLiPC lipids and aliphatic solutes (averaged over the last 100 ns of simulation at low solute concentration, 295 K) expressed as relative density and normalized solute density . Right panels: snapshots from the same simulations, side view. Only one particle per lipid is shown; phosphate group is colored in red for DLiPC and in blue for DPPC, cholesterol hydroxyl group is in yellow, solutes in gray.
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phase separationaliphatic compoundsdomain stabilizationmodel membranesprotein traffickingmodel systemsmembrane domainsmacroscopic phase separationlipophilic compounds perturb membrane domainsdomain stabilitySignal transductiondomain perturbationlipophilic compoundsHydrophobic Compounds Reshape Membrane Domains Cell membranes
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