A subset of nucleosomes demonstrate behaviors specific to H3 depletion.
2012-06-21T00:03:48Z (GMT) by
<p>(A) Schematic representation of the nucleosome classification method. Nucleosomes were classified based on changes in center positions and changes in read center counts between 0 hours and 3 hours (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002771#s4" target="_blank">Materials and Methods</a>). (B) Classification of nucleosomes. The number of nucleosomes in each classification that occur in only the wildtype strain 3 hours after the shift to Galactose (black); only the H3 shutoff strain (white); and those classified identically in both strains (gray) is shown. Only the H3 shutoff-specific nucleosomes (white) were used in subsequent analyses. The total number of nucleosomes that could be classified in each category are as follows: wildtype, 43,508; H3 shutoff, 38,955; classified in both, 28,717.</p>