Figure_7.tif (326.56 kB)
A proposed model for the molecular mechanism through which LicA inhibits HCC cell migration and invasion.
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posted on 2014-01-22, 03:47 authored by Jen-Pi Tsai, Pei-Ching Hsiao, Shun-Fa Yang, Shu-Ching Hsieh, Da-Tian Bau, Chu-Liang Ling, Chun-Li Pai, Yi-Hsien HsiehLicA inhibits uPA expression and subsequent cancer cell migration and invasion through a downregulation of the MKK4/JNK signaling pathway and NF-κB transcriptional activation.