(A) Schematic representation of the L. migratoria and O. furnacalis Notch.

The domain organization was predicted using the SMART program (http://smart.embl.de/). Question mark means the end is incomplete. (B) Phylogenetic analysis of the Notch from insects, hydrobios and vertebrates. The unrooted tree was generated using the distance-based method Neighbor-Joing, with Caenorhabditis elegans protein as outgroup. The branch lengths reflect evolutionary divergence. The circled bootstrap value indicates that L. migratoria a1269 and O. furnacalis Unigene6905 (marked in red) belong to insect Notch group.