ol7b01578_si_002.pdf (13.28 MB)
(3 + 2)-Annulation of p‑Quinamine and Aryne: A Strategy To Construct the Multisubstituted Hydrocarbazoles
journal contribution
posted on 2017-06-28, 12:40 authored by Dengyu Xu, Yulong Zhao, Dengpeng Song, Zhuliang Zhong, Shangbiao Feng, Xingang Xie, Xiaolei Wang, Xuegong SheA strategy
for the synthesis of multisubstituted hydrocarbazoles
has been developed through (3 + 2)-annulation of p-quinamines and arynes. In this way, new analogs of hydrocarbazoles
with quaternary carbon center can be synthesized in satisfactory yield
under mild conditions. Furthermore, this (3 + 2)-annulation can be
easily scaled-up, and the products can be modified through simple
transformation.