Water Exclusion Reaction in Aqueous Media: Nitrone Formation and Cycloaddition in a Single Pot
2003-09-17T00:00:00Z (GMT) by
The formation of nitrone (a water exclusion reaction) in aqueous media using surfactant and subsequent cycloaddition in the same pot, a new example of green chemistry, is reported. The control of regioselectivity favors the formation of trans<i>-</i>5-substituted isoxazolidine. This work not only may lead to an environmentally benign system but also will provide a new aspect of reactions in water.