V67A and P145A disrupted the co-localization between NS5A and Core or LDs.

<p><b>A</b> Quantification of the percentages of NS5A colocalized with LD (white blocks), or LD colocalised with NS5A (red blocks). <b>B</b> Quantification of the percentages of NS5A colocalized with Core (white blocks), or Core colocalised with NS5A (green blocks). <b>C</b> Quantification of the percentages of Core colocalized with LD (green blocks), or LD colocalised with Core (red blocks). <b>D</b> Spatial data for the distance of LDs from the nuclear envelope were determined from 10 cells for each construct using Fiji. **** indicates significant difference (P<0.0001) from the results for WT.</p>