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Using diversity to measure boundaries of the pseudoautosomal regions in human sex chromosomes

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posted on 25.06.2015 by Sarah Brotman, Daniel Cotter, Logan Curtis-Whitchurch, Melissa Wilson Sayres

As opposed to autosomes, the human sex chromosomes do not recombine across their entire length. However, there are two small regions on the X and Y chromosomes called pseudoautosomal regions (PARs) that recombine during male meiosis. Because pairing can only occur in the PARs, we expect large differences in diversity between the PAR and non-PAR regions. In this research we aim to use the difference in diversity between the regions to identify the location of the boundary between recombining and non-recombining regions on the human X chromosome.

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