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Two new phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity

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posted on 2017-03-28, 09:25 authored by Yan-gang Cao, Xiao-ke Zheng, Fang-fang Yang, Fang Li, Man Qi, Yan-li Zhang, Xuan Zhao, Hai-xue Kuang, Wei-sheng Feng

A new biphenyl-furocoumarin, named morescoumarin A (1), and a new prenylated flavanone, named morflavanone A (2) were isolated from the root bark of Morus alba L., together with four known compounds (3–6). Their structures were determined by extensive spectroscopic analyses and comparison with literature data. The cardioprotective effects of these compounds against doxorubicin-induced cell death were evaluated by MTT method.

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