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Two new chalcones from Shuteria sinensis

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Version 2 2015-10-08, 11:39
Version 1 2015-10-08, 11:39
journal contribution
posted on 2015-10-08, 11:39 authored by Zhuya Yang, Xiaoxia Ma, Wenhong Tan, Libin Zhou, Xinying Zhuang, Shude Yang, Zigang Qian, Zhihong Zhou

Two new chalcones, 2′,3,4,4′-tetrahydroxy-2-prenylchalcone (1) and 3-methoxy-2′,4,4′-trihydroxy-2-prenylchalcone (2), together with two known compounds, munsericin (3) and 3,4-dihydroxylonchocarpin (4), were isolated from the ethanol extract of the whole plant of Shuteria sinensis. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with HR-MS data. Glucose metabolism activity of four compounds was tested, compounds 3 and 4 showed effect on the glucose consumption of insulin-resistant HepG2 cells.

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