Two new anthraquinone derivatives and one new triarylbenzophenone analog from <i>Selaginella tamariscina</i>

<p>Two new anthraquinone derivatives, selaginones A (<b>1</b>) and B (<b>2</b>), and one new triarylbenzophenone analog, selagibenzophenone B (<b>3</b>), were isolated from <i>Selaginella tamariscina</i> (Beauv.) Spring. Their structures were established by 1D-, 2D-NMR and HR-ESI-MS data. Compounds <b>1</b> and <b>2</b> represent the uncommon examples of aryl substituted anthraquinone derivatives. Especially, compound <b>2</b> is a unique anthranone with exceptional structural feature, in which a <i>p</i>-hydroxyphenyl moiety is attached to the C-10 position. Compound <b>3</b> is the second naturally occurring triarylbenzophenone and showed moderate activity against SMCC-7721 and MHCC97-H cell lines with IC<sub>50</sub> values of 39.8, 51.5 μM respectively.</p>