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Two loci with genome-wide significant age-joint effects on late AMD which were undetected by Fritsche et al.

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posted on 2018-03-12, 17:51 authored by Thomas W. Winkler, Caroline Brandl, Felix Grassmann, Mathias Gorski, Klaus Stark, Julika Loss, Bernhard H. F. Weber, Iris M. Heid

Shown are the two lead variants with genome-wide significant joint-effects on late AMD (PAgejoint < 5 x 10−8) for the two loci that were not detected in the previous genome-wide screen by Fritsche et al [13]. Age-stratified analyses included 17,031 younger (7,959 cases, 9,072 controls) and 16,587 older (7,934 cases, 8,653 controls) individuals.

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