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Tributylphosphine-Catalyzed Cycloaddition of Aziridines with Carbon Disulfide and Isothiocyanate

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posted on 2008-11-21, 00:00 authored by Jing-Yu Wu, Zhi-Bin Luo, Li-Xin Dai, Xue-Long Hou
Aziridines underwent cyclization reaction with carbon disulfide and isothiocyanate in the presence of organophosphine to afford thiazolidinone derivatives in good to high yields. The mechanistic study revealed that organophosphine serves as a catalyst in the reaction.

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