pcbi.1005869.s001.pdf (289.74 kB)

Steady state and time scale analysis of the Cand1 cycle model.

journal contribution

posted on 2017-11-17, 18:36 authored by Ronny Straube, Meera Shah, Dietrich Flockerzi, Dieter A. Wolf

In S1 Text we conduct a steady state / time scale analysis of Eq (3) and provide the derivations of Eqs (5)–(9).

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26 S proteasome cullin scaffold substrate receptors bind substrates Cand 1 cullin-RING ubiquitin ligase repertoire Cullin-RING ubiquitin ligases protein exchange factor substrate receptor abundances substrate receptors Cand 1 concentration CRL repertoire Cand 1-mediated exchange cycle

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