Total synthesis of Patulolide A <i>via</i> ring closing metathesis

<p>A simple and efficient total synthesis of Patulolide A from readily available 7-Octen-1-ol is reported by asymmetric synthetic approach. The key reactions involved are asymmetric dihydroxylation using AD-mix-β and Grubbs’ RCM reaction for the synthesis macrocyclic ring system”.</p>