Total Synthesis of Methyl Sarcophytoate

Together with the improved synthesis of the diene unit <b>15</b> of methyl sarcophytoate (<b>1</b>), a biscembranoid marine natural product, the asymmetric total synthesis of <b>1</b> was achieved by the thermal Diels−Alder reaction between the dienophile unit, methyl sarcoate (<b>2</b>), and <b>15</b>.