Time-dependent changes in the stress-induced anxiety-like behaviors in rats as determined by EPM and ETM.

<p>(A) Percent open arm entry, (B) percent open arm time, (C) percent closed arm entry, (D) percent closed arm time, and (E) total number of entries in 1-, 4-, and 8-week stressed male rats, as determined by elevated plus-maze (EPM). (F) One-way escape latency, (G) baseline time, (H) avoidance 1, and (I) avoidance 2 in stressed rats, as determined by elevated T-maze (ETM). Numbers of animals are noted in parentheses. *<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001 stress vs. control.</p>