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Time-dependent CD62P surface expression and fibrinogen binding of platelets in citrated WB.
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posted on 2017-11-20, 18:38 authored by Juergen Koessler, Michaela Schwarz, Katja Weber, Julia Etzel, Angela Koessler, Markus Boeck, Anna KobsarThe histograms show the mean fluorescence intensities (MFI) of basal (white columns) and 10 μM TRAP-6 stimulated (shaded columns) CD62P expression (A) or fibrinogen binding (B) in fresh PB and in stored WB units at different time points as indicated. Results are presented in absolute arbitrary units (AU) as mean fluorescence ± SEM; n = 5; *: p < 0.05 (stimulated values compared to basal values); **: p < 0.05 (compared to PB and to WB at day 0).
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adenosine diphosphateWBvivo conditions Background Plateletspurinergic receptor expressionplatelet responsivenesspurinergic receptor P 2Y activityday 5. Conclusionbasal vasodilator-stimulated phosphoprotein5 daysP 2Y activityInhibitory pathwaysPurinergic receptor expressionTRAPPBObjectives Platelet integritystoragelight transmission aggregometryP 2X functionplatelet integrityVASPCD 62P expressionADP-mediated platelet integrity
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