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The specific lytic activity of MCF-7 cancer stem-like cell antigens.

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posted on 2018-01-03, 18:38 authored by Yoo Jin Choi, Seong-Joon Park, You-Soo Park, Hee Sung Park, Kwang Mo Yang, Kyu Heo

(A) Identification of populations of MCF-7 cells by flow cytometry analysis of CD44 and CD24 expression. (B) Western blot showing CD44 and ALDH protein expression in CD44+, CD44- and CD44+CD24- MCF7- cells. (C) Targeted killing of CD44+ MCF-7 cells by tumor-associated antigen-pulsed, DC-induced CTLs. The data are expressed as the mean±SD, and significant differences between the treated groups were detected using ANOVA followed by the Dunnett’s test. # p<0.05 compared with the DC-CTLs. * p<0.05 compared with the TL-CTLs.

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