The brain nodes significantly differing in MCI and AD.
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posted on 2017-11-14, 18:27 authored by Javier Rasero, Nicola Amoroso, Marianna La Rocca, Sabina Tangaro, Roberto Bellotti, Sebastiano StramagliaTheir patches correspond to the following anatomical structures: (A) left hemisphere: Hippocampus, Amygdala, Planum Polare; (B) left hemisphere: Parahippocampal Gyrus; (C) right hemisphere: Parahippocampal Gyrus; (D) right hemisphere: Hippocampus, Amygdala, Planum Polare; (E) left hemisphere: Frontal Orbital Cortex, Temporal Pole; (F) Inter-hemispheric: Subcallosal Cortex. (G) right hemisphere: Frontal Orbital Cortex, Temporal Pole; (H) left hemisphere: Subcallosal Cortex. Green patches are significant for both ncMCI and cMCI, whilst red patches are significant only for ncMCI.
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Temporal PolecMCI subjectsmultivariate distance matrix regressionconnectivity patternMDMRcomparisons AD-ncMCI549 regionsbrain regionsbrain areaADNIPlanum PolareMR imagesParahippocampal Gyrusimage similarityconnectivity mapsdisease-severity progressionMRI connectivity matricesFrontal Orbital Cortexbrain atrophynodes formconnectivity patternsMultivariate regression analysisMRI connectivitysubcallosal cortexgroup comparisonHCbrain network dataAD subjectspattern w.r.tbrain nodesbrain regionncMCI subjectsMRI brain networksMCI stages
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