The Rhea SPARQL endpoint supports integrated analyses of genome, proteome and metabolome
2018-12-01T07:54:11Z (GMT) by
‘Omics technologies enable comprehensive analyses of how genetic variation (genomics), gene expression patterns (transcriptomics), proteins and complexes (proteomics), and<br>small molecules (metabolomics) interact in complex biological systems. RDF and SPARQL can connect these ‘omics domains and help us realize the full potential of this valuable experimental data.<br>Rhea is a comprehensive and non-redundant resource of expert-curated biochemical reactions based on the ChEBI ontology. Here we demonstrate how to link genome (Ensembl), proteome (UniProt), and metabolome (ChEBI) data using federated queries that leverage the SPARQL<br>endpoint of Rhea (https://sparql.rhea-db.org/sparql) and data from these other resources.