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HuynhPacificPhDThesis30April2018.pdf (26.2 MB)

The Pathological Role of Cell Division Autoantigen 1 (CDA1) in renal fibrosis

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posted on 2018-07-09, 00:39 authored by PACIFIC HUYNH
Cell Division Autoantigen 1 (CDA1) has been validated as a potential target to treat diabetic patients with kidney disease. My project was to further examine the role of CDA1 in a scenario similar to the clinical setting were I experimentally targeted CDA1 after the disease has been established. Indeed, my study confirms that targeting CDA1 at early stages of diabetic kidney disease was effective in reducing kidney scarring in experimental diabetic mice.

History

Principal supervisor

Mark Emmanuel Cooper

Additional supervisor 1

Dr Zhong-Lin Chai

Year of Award

2018

Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Immunology - Alfred

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Keywords

    Renal FibrosisTransforming growth factor beta (TGFβ)Cell Division Autoantigen 1 (CDA1)Diabetic NephropathyInducible Genetic DeletionPathologyBiochemistry and Cell Biology not elsewhere classified

    Licence

    In Copyright

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