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Tead-regulated genes in C2C12 cells.

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posted on 2017-02-08, 18:48 authored by Shilpy Joshi, Guillaume Davidson, Stéphanie Le Gras, Shuichi Watanabe, Thomas Braun, Gabrielle Mengus, Irwin Davidson

A. Schematic outline of the experimental design and box plots showing gene expression changes during differentiation of cells transfected with siTead1/4. B. Examples of genes deregulated in siTead1/4 cells compared to siControl. C. GSEA analyses of Tead1/4 regulated genes. The most significant categories in the up- and down-regulated genes sets are shown. D. Tead4 sites preferentially occupied in differentiated cells and associated with expressed genes are depicted in a read density map alongside a heat hap of gene expression following siTead1/4 knockdown.

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