Tead-regulated genes in C2C12 cells.

<p><b>A.</b> Schematic outline of the experimental design and box plots showing gene expression changes during differentiation of cells transfected with <i>siTead1/4</i>. <b>B.</b> Examples of genes deregulated in <i>siTead1/4</i> cells compared to siControl. <b>C.</b> GSEA analyses of Tead1/4 regulated genes. The most significant categories in the up- and down-regulated genes sets are shown. <b>D.</b> Tead4 sites preferentially occupied in differentiated cells and associated with expressed genes are depicted in a read density map alongside a heat hap of gene expression following si<i>Tead1/4</i> knockdown.</p>