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Synthetic Studies and Mechanistic Insight in Nickel-Catalyzed [4+2+1] Cycloadditions
journal contribution
posted on 2006-03-01, 00:00 authored by Yike Ni, John MontgomeryA new nickel-catalyzed procedure for the [4+2+1] cycloaddition of (trimethylsilyl)diazomethane
with alkynes tethered to dienes has been developed. A broad range of unsaturated substrates participate
in the sequence, and stereoselectivities are generally excellent. Stereochemical studies provided evidence
for a mechanism that involves the [3,3] sigmatropic rearrangement of divinylcyclopropanes.