Synthesis of the Indolizino[7,6-<i>c</i>]quinoline Alkaloid Isaindigotidione

2010-10-15T00:00:00Z (GMT) by Malik Hellal Gregory D. Cuny
The first synthesis of isaindigotidione has been developed utilizing a reaction sequence including an asymmetric rhodium-catalyzed 1,4-conjugate addition, an intramolecular aldol reaction, and a lactamization.