lsyc_a_1252045_sm0062.docx (2.52 MB)
Synthesis of 4-phenyloxazinones via DBU-catalyzed cleavage of 4-bromomethylcoumarins
Version 2 2016-12-16, 13:31
Version 1 2016-11-02, 14:40
journal contribution
posted on 2016-12-16, 13:31 authored by Devadas Shamala, Kalegowda ShivashankarA new route for ring transformation has been discovered during the reaction of 4-bromomethylcoumarins with hydroxyl amine in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), leading to the formation of pharmacologically important 1,2-oxazinones in a single step with very high yields.