Synthesis of 3-(3-(Phenacyl/Alkyl/Benzylthio)-[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl)-2<i>H</i>-Chromen-2-Ones

2014-01-01T00:00:00Z (GMT) by Rajeswar Rao Vedula Sreenu Pavurala
<div><p></p><p>Reaction of coumarin-3-carboxylic acid with 3,5-di mercapto-4-amino-s-triazole in POCl<sub>3</sub>to generate 3-(3-mercapto-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2H-chromen-2-one (<b>3</b>). Reaction of <b>3</b> with different substituted phenacyl/benzyl/allyl bromides in anhydrous ethanol gave corresponding 3-(3-(phenacyl/alkyl/benzylthio)-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazol-6-yl)-2H-chromen-2-ones <b>5</b>. The structures of newly prepared compounds were confirmed by their analytic and spectral data.</p> </div>

Categories

Keyword(s)

License

CC BY 4.0