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Surface-enhanced Raman on gold nanoparticles for the identification of the most common adulterant of Astragali Radix

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posted on 2018-09-28, 13:09 authored by Hongxin Lin, Ying Chen, Shangyuan Feng, Weiwei Chen, Duo Lin, Hao Huang, Jia Lin, Rong Chen, Guannan Chen, Yun Yu

Adulterant is a common problem in Astragali Radix (a widely used Chinese herbal medicine). In this study, the surface-enhanced Raman technique was used to identify the authentic Astragali Radix and the most common adulterant with the aim to develop a convenient and sensitive method for the adulterant identification. Surface-enhanced Raman spectra combined with multivariate diagnostic algorithm differentiated the authentic Astragali Radix from the adulterant with high sensitivity (100%) and specificity (97.6%). This exploratory work demonstrates that surface-enhanced Raman technology can be used for the rapid and label-free screening of adulterant and has great potential for the quality control of Chinese herbal.

Funding

This study was supported by the National Natural Science Foundation of China [Nos. 61575043 and 81741008], the Strait United Foundation [No. U1605253], the Natural Science Foundation of Fujian Province of China [Nos. 2017J01844, 2017J01843, 2017J01499, and 2018J01876], and the distinguished young researcher of universities of Fujian province of China.

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