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Supplementary Material for: Genetic Factors Associated with Age-Related Macular Degeneration
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posted on 2011-07-14, 00:00 authored by Leveziel N., Tilleul J., Puche N., Zerbib J., Laloum F., Querques G., Souied E.H.Age-related macular degeneration (AMD) is a complex, multifactorial disease associated with environmental and genetic factors. This review emphasizes the clinical impact of the major genetic factors mainly located in the complement factor H gene and on the 10q26 locus, and their current and future implications for the management of AMD.
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Age-related macular degenerationAge-related maculopathyGenetic factorsPersonalized medicineMissing heritabilityGenome-wide association studiesAtrophic age-related macular degenerationExudative age-related macular degenerationComplement factor H gene (CFH)LOC387715Age-related maculopathy susceptibility 2 gene (ARMS2)HtrA serine peptidase 1 gene (HTRA1)Complement component 2, 3, 9 (C2, C3, C9)Genetic profilingAsian
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