Supplementary Figures from A eukaryotic nicotinate-inducible gene cluster: convergent evolution in fungi and bacteria

Supplementary Figures S1, S2, S3 and S4. Fig. S1: Phenotypes of hxnS- mutations. Fig. S2: Comparison of the modelled substrate binding site of HxA and HxnS with that of the Bos taurus Xanthine dehydrogenase. Fig. S3: A Maximum Likelihood rooted tree of all available fungal XDH-like enzymes with Eukaryotic out-groups. Fig. S4: The results of a CONSURF alignment of HxnR with 123 putative orthologues.