eQTLs in the poly-unsaturated fat metabolism cluster

<div>Chromatin interactions (using Hi-C) and functional (using eQTL) data were used to identify long-range regulatory associations involving >20,000 GWAS variants and their target genes (i.e. eGenes). Convex biclustering was then used to segregate phenotypes that share eGenes, which implies a common underlying molecular mechanism. In the cluster that is built around the <i>FADS</i> locus, SNPs have inverse eQTL effects on <i>FADS1</i>, <i>FADS2</i>, and the other genes in the region. Here, the reference and alternate alleles of the SNP positions are given with their frequencies.</div>