Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

dataset

posted on 2018-06-13, 02:45 authored by Carlos Bernardo Tauil, Talyta Cortez Grippe, Ronaldo Maciel Dias, Rafael Paternò Castello Dias-Carneiro, Narel Moita Carneiro, Ana Carolina Rodrigues Aguilar, Flávia Martins da Silva, Felipe Bezerra, Leonardo Kenzo de Almeida, Vitoria Lana Massarente, Elaine de Carvalho Giovannelli, Charles Peter Tilbery, Carlos Otávio Brandão, Leonilda Maria B Santos, Leopoldo dos Santos-Neto

ABSTRACT Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. Methods: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale. Results: A hierarchical regression analysis was performed to evaluate the variables. The regression equation significantly predicted the BSI score (R2 = 0.306; adjusted R2 = 0.273; F (9, 125) = 9.18; p < 0.0005), and the BDI-II score was the only variable that contributed significantly to this model (p < 0.0005). Conclusions: A high prevalence of depression and anxiety, and a higher rate of suicidal ideation were identified in MS patients compared to the general population. The presence of depressive symptoms appeared to have a direct influence on the risk of suicide.