ol048544j_si_002.pdf (196.42 kB)
Substituted Epoxides by Lithiation of Terminal Epoxides
journal contribution
posted on 2004-11-11, 00:00 authored by David M. Hodgson, Nigel J. Reynolds, Steven J. CooteDiamine-ligand-assisted direct hydrogen−lithium exchange allows the generation of nonstabilized (H-substituted) oxiranyllithium species and
their subsequent trapping by Bu3SnCl and carbonyl-based electrophiles. This reaction provides a new concise route to α,β-epoxystannanes
and substituted epoxides.