pone.0197204.g001.tif (661.03 kB)
Study design flow diagram illustrating enrollment, data collection, treatment and analysis.
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posted on 2018-06-19, 20:03 authored by Susannah J. Sample, Molly A. Racette, Eric C. Hans, Nicola J. Volstad, Susan L. Schaefer, Jason A. Bleedorn, Jeffrey P. Little, Kenneth R. Waller III, Zhengling Hao, Walter F. Block, Peter MuirPRP—platelet rich plasma; TPLO—tibial plateau leveling osteotomy for treatment of stifle instability from CR; MRI—magnetic resonance imaging.
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cranial cruciate ligamentC-reactive proteinligament fiber12- month follow-up periodcohort studycruciate ligament ruptureRadiographic effusionhistologic evaluation3.0 TeslaOAdisease-modifying therapysynovial biopsiesCRParthroscopic evaluationdogs DogsMR assessmentbioenhanced repair treatment29 client-owned dogscontralateral CR12- monthstibial plateau leveling osteotomy12- month study periodPRPsynovial fluidTPLOgrowth factorscell countplatelet-rich plasma-collagen scaffoldintra-articular collagen scaffoldcollagen scaffolddisease progressionintra-articular application10- weeks
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