ol060882s_si_001.pdf (6.39 MB)
Studies toward Soraphen A: An Aldol−Metathesis Avenue to the Macrocyclic Framework
journal contribution
posted on 2006-06-22, 00:00 authored by Guillaume Vincent, Darren J. Mansfield, Jean-Pierre Vors, Marco A. CiufoliniWe describe a convergent approach to soraphen A, 1, that involves coupling of two fragments by an aldol condensation−olefin metathesis
sequence. This route permits rapid access to congeners of 1.