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Studies toward Soraphen A:  An Aldol−Metathesis Avenue to the Macrocyclic Framework

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posted on 2006-06-22, 00:00 authored by Guillaume Vincent, Darren J. Mansfield, Jean-Pierre Vors, Marco A. Ciufolini
We describe a convergent approach to soraphen A, 1, that involves coupling of two fragments by an aldol condensation−olefin metathesis sequence. This route permits rapid access to congeners of 1.

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