Structure and Absolute Configuration of Helosides A and B, New Saponins from <i>Chamaelirium luteum</i>

Investigation of <i>Chamaelirium luteum</i> roots led to the isolation of two new steroidal saponins, helosides A (<b>1</b>) and B (<b>2</b>), that contain a previously unreported aglycone, helogenin (<b>3</b>). Their structures and absolute configuration were elucidated through MS-MS, NMR, chemical degradation, and X-ray crystallography.