Stochastic property of endoreduplication.

(A) The measured size of EPCs plotted against the corresponding ploidy level represented as the C value, which indicates DNA content estimated by a 4’,6-diamidino-2-phenylindole (DAPI)-based imaging technique [28]. Data on 2C (green), 4C (blue), 8C (orange), 16C (red), and 32C (black) are shown. This figure is essentially the same as Fig 2C in Katagiri et al., 2016 [28]. (B) Steady-state probability of the occurrence of endoreduplication in vivo (gray bars). For example, if endoreduplication occurs four times in a given time period, the ploidy level reaches 32C. The data fit a Poisson distribution (dashed line) with an average of 1.12 rounds.