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Stereo views of cocrystal structures-Ahmed-Belkacem et al.pdf (43.86 MB)

Stereo views of cocrystal structures of cyclophilins with cyclophilin inhibitors.pdf

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Version 3 2016-07-16, 17:08
Version 2 2016-07-16, 17:02
Version 1 2016-07-04, 12:08
journal contribution
posted on 2016-07-16, 17:08 authored by Jean-Michel PawlotskyJean-Michel Pawlotsky, abdelhakim ahmed-belkacem, lionel colliandre, nazim ahnou, quentin nevers, muriel gelin, yannick bessin, rozenn brillet, olivier cala, dominique douguet, william bourguet, isabelle krimm, jean-francois guichou
Cocrystal structures (stereo views of sections of the electron density maps) of cyclophilin D complexed with different compounds from a new family of nonpeptidic, small-molecule cyclophilin inhibitors

Funding

This work was supported by the French Infrastructure for Integrated Structural Biology (FRISBI) ANR-10-INSB-05-01, the Fonds Européen de Développement Économique et Régional (FEDER) N°48748, the ANRS

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    Keywords

    cyclophilininhibitorshepatitis C viruscoronavirusfragment based drug discoverycocrystal structuresInfectious AgentsCrystallographyNMR SpectroscopyStructural Chemistry and Spectroscopy

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