Six month-old male whole body glucose, insulin and pyruvate tolerance.

<p>Whole body tolerance tests were completed on fasted 6 month-old male wildtype (WT), aromatase knockout (KO) and 2.5 µg/kg 17β-estradiol-treated KO (KOE). (<b>a</b>) Glucose tolerance test and corresponding area under curve; (<b>b</b>) insulin tolerance test and corresponding area under curve; (<b>c</b>) pyruvate tolerance test and corresponding area under curve. Data are presented from replicate analysis (n =  shown on corresponding bar) as the mean ± SD. <i>*p&lt;0.05, **p&lt;0.01</i>, versus expression in age-matched WT samples and <i><sup>#</sup>p&lt;0.05 and <sup>##</sup>p&lt;0.01</i> versus KO samples</p>