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Short chain fatty acids are abundant in the CF airways.

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posted on 2016-08-22, 04:30 authored by Jeffrey M. Flynn, David Niccum, Jordan M. Dunitz, Ryan C. Hunter

(A) Direct measurements of (A) acetate and (B) propionate in paired sputum and saliva samples from CF patients. Acetate concentrations were significantly higher in sputum (**, p = 0.004).

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    PLOS Pathogens

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    carbon fluxairway diseasepropionateCF patientsCF lung microbiotabacteriaexpectorated sputumcarbon sourcefermentative metabolismaeruginosa gene expressionvivo P16 S rRNA sequencingmucinairway damageCF pathogensenrichment culturingBacterial Mucin DegradationPseudomonas aeruginosacarbon reservoirCystic Fibrosis Airway Disease Chronic lung infections

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